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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620241
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lef1
Name: lymphoid enhancer binding factor 1
Acc ID: CHEBI:31941
Term: oxaliplatin
Definition: A platinum coordination entity that is a commonly used chemothrepeutic drug for treatment of colorectal cancer.
Chemical ID: MESH:C030110
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lef1multiple interactionsEXP 6480464CTD[oxaliplatin co-treated with Topotecan] results in decreased expression of LEF1 mRNAPMID:25729387
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