GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | NQO1 | decreases expression | EXP | | 6480464 | CTD | Mercuric Chloride results in decreased expression of NQO1 protein | PMID:37172713 | NQO1 | increases expression | EXP | | 6480464 | CTD | Mercuric Chloride results in increased expression of NQO1 mRNA | PMID:21843634 PMID:26272509 PMID:27188386 | NQO1 | multiple interactions | EXP | | 6480464 | CTD | [NOG protein co-treated with Mercuric Chloride co-treated with dorsomorphin co-treated with 4-(5-benzo(1,3)dioxol-5-yl-4-pyridin-2-yl-1H-imidazol-2-yl)benzamide] results in increased expression of NQO1 mRNA; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [sulforaphane results in increased expression of NQO1 mRNA]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of and results in increased activity of NQO1 protein]; Mercuric Chloride promotes the reaction [Tetrachlorodibenzodioxin results in increased expression of NQO1 mRNA]; Mercuric Chloride results in increased expression of and results in increased activity of NQO1 protein; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased activity of NQO1 protein]; NFE2L2 mRNA affects the reaction [Mercuric Chloride results in increased expression of NQO1 mRNA] | PMID:21843634 PMID:27188386 | NQO1 | decreases expression | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Mercuric Chloride results in decreased expression of NQO1 mRNA; Mercuric Chloride results in decreased expression of NQO1 protein | PMID:23202902 PMID:37172713 | NQO1 | increases activity | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | Mercuric Chloride results in increased activity of NQO1 protein | PMID:18838692 | NQO1 | multiple interactions | ISO | Nqo1 (Mus musculus) | 6480464 | CTD | [Dimercaprol co-treated with Mercuric Chloride] results in increased activity of NQO1 protein | PMID:18838692 | |
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