Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620640
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2d4
Name: cytochrome P450, family 2, subfamily d, polypeptide 4
Acc ID: CHEBI:31821
Term: Mequitazine
Definition: A phenothiazine that has formula C20H22N2S.
Chemical ID: MESH:C006069
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2d4increases hydroxylationISORGD:7362176480464CTDCYP2D6 protein results in increased hydroxylation of mequitazine

PMID:15863898
Cyp2d4multiple interactionsISORGD:7362176480464CTDNicardipine inhibits the reaction [CYP2D6 protein results in increased hydroxylation of mequitazine]

PMID:15863898
Go Back to source page   Continue to Ontology report