GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Drd2 | affects response to substance | EXP | | 6480464 | CTD | DRD2 protein affects the susceptibility to Bromocriptine | PMID:8103596 | Drd2 | decreases expression | EXP | | 6480464 | CTD | Bromocriptine results in decreased expression of DRD2 mRNA | PMID:15781964 | Drd2 | multiple interactions | EXP | | 6480464 | CTD | Bromocriptine binds to and results in increased activity of DRD2 mRNA; Bromocriptine promotes the reaction [Clozapine results in decreased expression of DRD2 mRNA] | PMID:1534540 PMID:15781964 | Drd2 | affects expression | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | Bromocriptine affects the expression of DRD2 mRNA | PMID:20063113 | Drd2 | decreases expression | ISO | Drd2 (Mus musculus) | 6480464 | CTD | Bromocriptine results in decreased expression of DRD2 mRNA | PMID:15781964 | Drd2 | increases expression | ISO | Drd2 (Mus musculus) | 6480464 | CTD | Bromocriptine results in increased expression of DRD2 mRNA | PMID:15781964 | Drd2 | increases response to substance | ISO | DRD2 (Homo sapiens) | 6480464 | CTD | DRD2 polymorphism results in increased susceptibility to Bromocriptine | PMID:16901644 | Drd2 | multiple interactions | ISO | Drd2 (Mus musculus) | 6480464 | CTD | [Clozapine co-treated with Bromocriptine] results in decreased expression of DRD2 mRNA | PMID:15781964 | |
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