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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620436
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cga
Name: glycoprotein hormones, alpha polypeptide
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases activityISORGD:7318386480464CTDlead acetate results in decreased activity of CGA protein

PMID:11213355
multiple interactionsISORGD:7318386480464CTDlead acetate inhibits the reaction [CGA protein results in increased abundance of Progesterone]

PMID:11213355, PMID:12647776
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.