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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1307751
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Srebf2
Name: sterol regulatory element binding transcription factor 2
Acc ID: CHEBI:31767
Term: lead diacetate
Definition: A lead coordination entity in which a central lead(2+) atom is coordinated to two acetate ions.
Chemical ID: MESH:C008261
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Srebf2increases expressionEXP 6480464CTDlead acetate results in increased expression of SREBF2 mRNA; lead acetate results in increased expression of SREBF2 proteinPMID:29908845
Srebf2increases expressionISOSREBF2 (Homo sapiens)6480464CTDlead acetate results in increased expression of SREBF2 proteinPMID:34842334
Srebf2multiple interactionsISOSREBF2 (Homo sapiens)6480464CTDSRT1720 inhibits the reaction [lead acetate results in increased expression of SREBF2 protein]PMID:34842334
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