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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733741
Species: Homo sapiens
RGD Object: Gene
Symbol: GRIK4
Name: glutamate ionotropic receptor kainate type subunit 4
Acc ID: CHEBI:31746
Term: kainic acid
Definition: A pyrrolidinecarboxylic acid that has formula C10H15NO4.
Chemical ID: MESH:D007608
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
GRIK4decreases expressionISOGrik4 (Mus musculus)6480464CTDKainic Acid results in decreased expression of GRIK4 mRNAPMID:21589914
GRIK4multiple interactionsISOGrik4 (Mus musculus)6480464CTD[Celecoxib co-treated with Kainic Acid] results in decreased expression of GRIK4 mRNA; Kainic Acid promotes the reaction [cyanoginosin LR affects the localization of GRIK4 protein]PMID:21589914 PMID:34352349
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