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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311192
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Map3k4
Name: mitogen activated protein kinase kinase kinase 4
Acc ID: CHEBI:31739
Term: josamycin
Definition: A macrolide antibiotic produced by certain strains of Streptomyces narbonensis var. josamyceticus.
Chemical ID: MESH:D015570
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Map3k4decreases response to substanceISOMAP3K4 (Homo sapiens)6480464CTDMAP3K4 protein results in decreased susceptibility to JosamycinPMID:31915244
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