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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1595919
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp3a62
Name: cytochrome P450, family 3, subfamily a, polypeptide 62
Acc ID: CHEBI:31677
Term: hydrocortisone succinate
Definition: A derivative of succinic acid in which one of the carboxy groups is esterified by the C-21 hydroxy group of cortisol (hydrocortisone).
Chemical ID: MESH:C007133
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp3a62multiple interactionsISORGD:13529626480464CTD[hydrocortisone hemisuccinate co-treated with Dimethyl Sulfoxide] results in increased expression of CYP3A4

PMID:18347083
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