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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1311415
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Eef1b2
Name: eukaryotic translation elongation factor 1 beta 2
Acc ID: CHEBI:31653
Term: glafenine
Definition: A carboxylic ester that is 2,3-dihydroxypropyl anthranilate in which the amino group is substituted by a 7-chloroquinolin-4-yl group. A non-steroidal anti-inflammatory drug, glafenine and its hydrochloride salt were used for the relief of all types of pain, but high incidence of anaphylactic reactions resulted in their withdrawal from the market.
Chemical ID: MESH:D005897
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDGlafenine results in increased expression of EEF1B2 mRNA

PMID:24136188
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.