GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Areg | decreases expression | ISO | AREG (Homo sapiens) | 6480464 | CTD | Fulvestrant results in decreased expression of AREG mRNA | PMID:16202921 PMID:16514628 PMID:26865669 PMID:31646340 | Areg | increases expression | ISO | AREG (Homo sapiens) | 6480464 | CTD | fulvestrant results in increased expression of AREG mRNA | PMID:15072547 | Areg | multiple interactions | ISO | AREG (Homo sapiens) | 6480464 | CTD | Fulvestrant inhibits the reaction [4,4'-hexafluorisopropylidene diphenol results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [arsenite results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [Cadmium results in increased expression of AREG mRNA]; Fulvestrant inhibits the reaction [Estradiol results in increased expression of AREG mRNA] | PMID:31059536 PMID:31646340 | |
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