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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62043
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Xdh
Name: xanthine dehydrogenase
Acc ID: CHEBI:31623
Term: fluocinolone acetonide
Definition: A fluorinated steroid that is flunisolide in which the hydrogen at position 9 is replaced by fluorine. A corticosteroid with glucocorticoid activity, it is used (both as the anhydrous form and as the dihydrate) in creams, gels and ointments for the treatment of various skin disorders.
Chemical ID: MESH:D005446
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Xdhmultiple interactionsISOXdh (Mus musculus)6480464CTDFluocinolone Acetonide inhibits the reaction [Tetradecanoylphorbol Acetate results in increased activity of XDH protein]PMID:3677084
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