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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1624096
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp2c38
Name: cytochrome P450, family 2, subfamily c, polypeptide 38
Acc ID: CHEBI:31622
Term: flunitrazepam
Definition: A 1,4-benzodiazepinone that is nitrazepam substituted by a methyl group at position 1 and by a fluoro group at position 2'. It is a potent hypnotic, sedative, and amnestic drug used to treat chronic insomnia.
Chemical ID: MESH:D005445
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2c38increases metabolic processingISOCYP2C19 (Homo sapiens)6480464CTDCYP2C19 protein results in increased metabolism of FlunitrazepamPMID:10911933
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