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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69102
Species: Homo sapiens
RGD Object: Gene
Symbol: JAK1
Name: Janus kinase 1
Acc ID: CHEBI:31611
Term: Fidarestat
Definition: null
Chemical ID: MESH:C077139
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
JAK1decreases phosphorylationEXP 6480464CTDfidarestat results in decreased phosphorylation of JAK1 proteinPMID:21203431
JAK1multiple interactionsEXP 6480464CTDfidarestat inhibits the reaction [IL13 protein results in increased phosphorylation of JAK1 protein]PMID:21203431
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