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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 619996
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Bche
Name: butyrylcholinesterase
Acc ID: CHEBI:31529
Term: ecgonine methyl ester
Definition: The O-debenzoyl analogue of cocaine.
Chemical ID: MESH:C034524
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Bcheincreases abundanceISORGD:7321756480464CTDBCHE protein mutant form results in increased abundance of ecgonine methyl esterPMID:25814464
Bcheincreases chemical synthesisISORGD:7321746480464CTDBCHE protein mutant form results in increased chemical synthesis of ecgonine methyl esterPMID:30080993
Bchemultiple interactionsISORGD:7321746480464CTD[BCHE protein mutant form results in increased metabolism of Cocaine] which results in increased chemical synthesis of ecgonine methyl esterPMID:30080993
Bchemultiple interactionsISORGD:7321756480464CTD[BCHE protein mutant form results in increased hydrolysis of Cocaine] which results in increased abundance of ecgonine methyl esterPMID:25814464
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