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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2958
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Kcnj3
Name: potassium inwardly-rectifying channel, subfamily J, member 3
Acc ID: CHEBI:31526
Term: (S)-duloxetine hydrochloride
Definition: A duloxetine hydrochloride in which the duloxetine moiety has S configuration.
Chemical ID: MESH:D000068736
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Kcnj3multiple interactionsISOKcnj3 (Mus musculus)6480464CTDDuloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ5 mRNA]; Duloxetine Hydrochloride results in decreased activity of [KCNJ3 mRNA co-treated with KCNJ6 mRNA]PMID:22164246
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