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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 628725
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Homer1
Name: homer scaffold protein 1
Acc ID: CHEBI:31445
Term: cyclic ADP-ribose
Definition: A cyclic purine nucleotide that is synthesised from NAD+ by ADP-ribosyl cyclase; acts as an agonist at ryanodine receptors.
Chemical ID: MESH:D036563
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Homer1multiple interactionsEXP 6480464CTDHOMER1 protein alternative form inhibits the reaction [Cyclic ADP-Ribose promotes the reaction [RYR2 protein results in increased secretion of Calcium]]

PMID:12887973
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