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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 708428
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Akr1c3
Name: aldo-keto reductase family 1, member C3
Acc ID: CHEBI:31426
Term: cloxazolam
Definition: An oxazolobenzodiazepine that has formula C17H14Cl2N2O2.
Chemical ID: MESH:C005522
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c3decreases activityISORGD:13528886480464CTDcloxazolam results in decreased activity of AKR1C3 protein

PMID:11995921, PMID:12604236
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.