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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1353256
Species: Homo sapiens
RGD Object: Gene
Symbol: F2
Name: coagulation factor II, thrombin
Acc ID: CHEBI:31413
Term: clobazam
Definition: 7-Chloro-1H-1,5-benzodiazepine-2,4(3H,5H)-dione in which the hydrogen attached to the nitrogen at position 1 is substituted by a methyl group, whilst that attached to the other nitrogen is substituted by a phenyl group. It is used for the short-term management of acute anxiety and as an adjunct in the treatment of epilepsy in association with other antiepileptics.
Chemical ID: MESH:C012255
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
F2multiple interactionsEXP 6480464CTD[clobazam co-treated with Phenytoin] results in increased expression of [F2 protein binds to SERPINC1 protein]PMID:16376047
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