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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620007
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Cyp2j4
Name: cytochrome P450, family 2, subfamily j, polypeptide 4
Acc ID: CHEBI:31399
Term: cilnidipine
Definition: A diesterified 1,4-dihydropyridine-3,5-dicarboxylic acid. A calcium channel blocker, it is used as an antihypertensive.
Chemical ID: MESH:C065927
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp2j4decreases activityISORGD:13544676480464CTDcilnidipine results in decreased activity of CYP2J2 protein

PMID:30965050
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