Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733386
Species: Homo sapiens
RGD Object: Gene
Symbol: TGFBR1
Name: transforming growth factor beta receptor 1
Acc ID: CHEBI:3139
Term: bleomycin A2
Definition: A bleomycin that has formula C55H84N17O21S3.
Chemical ID: MESH:D001761
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
TGFBR1multiple interactionsEXP 6480464CTDMIR101-1 mRNA inhibits the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]PMID:28726637
TGFBR1increases expressionISOTgfbr1 (Mus musculus)6480464CTDBleomycin results in increased expression of TGFBR1 mRNAPMID:28726637
TGFBR1multiple interactionsISOTgfbr1 (Mus musculus)6480464CTD[CCL12 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [HIF1A protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]; [MMP3 protein co-treated with Dinoprostone] affects the reaction [Bleomycin results in increased expression of TGFBR1 mRNA]PMID:28434932
Go Back to source page   Continue to Ontology report