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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10326
Species: Mus musculus
RGD Object: Gene
Symbol: Cebpb
Name: CCAAT/enhancer binding protein beta
Acc ID: CHEBI:3139
Term: bleomycin A2
Definition: A bleomycin that has formula C55H84N17O21S3.
Chemical ID: MESH:D001761
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cebpbdecreases response to substanceEXP 6480464CTDCEBPB gene mutant form results in decreased susceptibility to BleomycinPMID:17177178
Cebpbincreases expressionEXP 6480464CTDBleomycin results in increased expression of CEBPB mRNAPMID:17177178
Cebpbincreases response to substanceEXP 6480464CTDCEBPB protein results in increased susceptibility to BleomycinPMID:21998664
Cebpbmultiple interactionsEXP 6480464CTDCEBPB protein affects the reaction [Bleomycin results in increased expression of ACTA2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of CCL2 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of IL1B mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TGFB1 mRNA]; CEBPB protein affects the reaction [Bleomycin results in increased expression of TNF mRNA]PMID:17177178
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