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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10438
Species: Mus musculus
RGD Object: Gene
Symbol: Cyp1a2
Name: cytochrome P450, family 1, subfamily a, polypeptide 2
Acc ID: CHEBI:31389
Term: chelidonine
Definition: An alkaloid antibiotic that has formula C20H19NO5.
Chemical ID: MESH:C062047
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Cyp1a2increases metabolic processingISOCYP1A2 (Homo sapiens)6480464CTDCYP1A2 protein results in increased metabolism of chelidoninePMID:31102647
Cyp1a2multiple interactionsISOCYP1A2 (Homo sapiens)6480464CTD[CYP1A2 protein results in increased metabolism of chelidonine] which results in increased abundance of Glutathione analogPMID:31102647
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