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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1321837
Species: Mus musculus
RGD Object: Gene
Symbol: Nfatc4
Name: nuclear factor of activated T cells, cytoplasmic, calcineurin dependent 4
Acc ID: CHEBI:31355
Term: carboplatin
Definition: A platinum coordination entity with cis square-planar geometry in which platinum(II) is coordinated to two ammonia ligands and a bidentate cyclobutane-1,1-dicarboxylate ligand.
Chemical ID: MESH:D016190
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfatc4increases activityEXP 6480464CTDCarboplatin results in increased activity of NFATC4PMID:21198546
Nfatc4multiple interactionsEXP 6480464CTDHMOX1 protein inhibits the reaction [Carboplatin results in increased activity of NFATC4]PMID:21198546
Nfatc4increases activityISONfatc4 (Rattus norvegicus)6480464CTDCarboplatin results in increased activity of NFATC4PMID:21198546
Nfatc4multiple interactionsISONfatc4 (Rattus norvegicus)6480464CTDHMOX1 protein inhibits the reaction [Carboplatin results in increased activity of NFATC4]PMID:21198546
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