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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1620115
Species: Mus musculus
RGD Object: Gene
Symbol: Gstp1
Name: glutathione S-transferase, pi 1
Acc ID: CHEBI:31276
Term: betamethasone dipropionate
Definition: A steroid ester that is betamethasone in which the hydroxy hydrogens at positions 17 and 21 are replaced by propanoyl groups. It is used in combination with calcipotriene hydrate, a synthetic vitamin D analogue, for the topical treatment of plaque psoriasis in adult patients.
Chemical ID: MESH:C011175
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gstp1multiple interactionsISOGSTP1 (Homo sapiens)6480464CTDbetamethasone-17,21-dipropionate inhibits the reaction [GSTP1 protein results in increased metabolism of 1-chloro-2,4-dinitrobenzene-glutathione conjugate]PMID:23769903
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