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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733541
Species: Mus musculus
RGD Object: Gene
Symbol: Egr2
Name: early growth response 2
Acc ID: CHEBI:31236
Term: aripiprazole
Definition: An N-arylpiperazine that is piperazine substituted by a 4-[(2-oxo-1,2,3,4-tetrahydroquinolin-7-yl)oxy]butyl group at position 1 and by a 2,3-dichlorophenyl group at position 4. It is an antipsychotic drug used for the treatment of Schizophrenia, and other mood disorders.
Chemical ID: MESH:C094645
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Egr2increases expressionISOEgr2 (Rattus norvegicus)6480464CTDAripiprazole results in increased expression of EGR2 mRNAPMID:17868501
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