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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 12328669
Species: Canis lupus familiaris
RGD Object: Gene
Symbol: PTGS1
Name: prostaglandin-endoperoxide synthase 1
Acc ID: CHEBI:31225
Term: antipyrine
Definition: A pyrazolone derivative that is 1,2-dihydropyrazol-3-one substituted with methyl groups at N-1 and C-5 and with a phenyl group at N-2.
Chemical ID: MESH:D000983
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
PTGS1decreases activityEXP 6480464CTDAntipyrine results in decreased activity of PTGS1 protein alternative formPMID:12242329
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