Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   


RGD ID: 619868
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gclc
Name: glutamate-cysteine ligase, catalytic subunit
Acc ID: CHEBI:31205
Term: amlexanox
Definition: A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Chemical ID: MESH:C045742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gclcincreases expressionISORGD:106526480464CTDamlexanox results in increased expression of GCLC mRNA

Gclcmultiple interactionsISORGD:106526480464CTD[Acetaminophen co-treated with amlexanox co-treated with dorsomorphin] affects the expression of GCLC mRNA, [Acetaminophen co-treated with amlexanox] affects the expression of GCLC mRNA

Go Back to source page   Continue to Ontology report


RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.