Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1308352
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Ikbke
Name: inhibitor of nuclear factor kappa B kinase subunit epsilon
Acc ID: CHEBI:31205
Term: amlexanox
Definition: A pyridochromene-derived monocarboxylic acid having an amino substituent at the 2-position, an oxo substituent at the 5-position and an isopropyl substituent at the 7-position.
Chemical ID: MESH:C045742
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Ikbkedecreases activityISORGD:13180726480464CTDamlexanox results in decreased activity of IKBKE protein

PMID:25321315
Ikbkemultiple interactionsISORGD:13180736480464CTDamlexanox inhibits the reaction [Acetaminophen results in increased phosphorylation of IKBKE protein]

PMID:31697998
Go Back to source page   Continue to Ontology report

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.