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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 735944
Species: Mus musculus
RGD Object: Gene
Symbol: Prkab2
Name: protein kinase, AMP-activated, beta 2 non-catalytic subunit
Acc ID: CHEBI:31175
Term: adefovir pivoxil
Definition: An organic phosphonate that is the dipivoxil ester of adefovir. A prodrug for adefovir, an HIV-1 reverse transcriptase inhibitor, adefovir pivoxil is used to treat chronic hepatitis B viral infection.
Chemical ID: MESH:C106812
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7359436480464CTDadefovir dipivoxil results in decreased expression of PRKAB2 mRNA

PMID:25596134
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.