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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 68486
Species: Homo sapiens
RGD Object: Gene
Symbol: AKR1A1
Name: aldo-keto reductase family 1 member A1
Acc ID: CHEBI:31059
Term: 13-dihydrodaunorubicin
Definition: An aminoglycoside antibiotic that is (1S,3S)-3,5,12-trihydroxy-3-(1-hydroxyethyl)-10-methoxy-6,11-dioxo-1,2,3,4,6,11-hexahydrotetracene having a 3-amino-2,3,6-trideoxy-alpha-L-lyxo-hexopyranosyl residue attached at position 1 via a glycosidic linkage.
Chemical ID: MESH:C000847
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
AKR1A1multiple interactionsEXP 6480464CTD[AKR1A1 results in increased metabolism of Daunorubicin] which results in increased chemical synthesis of daunorubicinolPMID:18276838
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