GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | PTGS2 | decreases expression | EXP | | 6480464 | CTD | isoliquiritigenin results in decreased expression of PTGS2 mRNA | PMID:23747687 | PTGS2 | multiple interactions | ISO | Ptgs2 (Rattus norvegicus) | 6480464 | CTD | isoliquiritigenin inhibits the reaction [Carbon Tetrachloride results in increased expression of PTGS2 protein] | PMID:25450236 | PTGS2 | multiple interactions | ISO | Ptgs2 (Mus musculus) | 6480464 | CTD | isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [[Azoxymethane co-treated with Dextran Sulfate] results in increased expression of PTGS2 protein]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 mRNA]; isoliquiritigenin inhibits the reaction [lipopolysaccharide, Escherichia coli O111 B4 results in increased expression of PTGS2 protein] | PMID:18295200 PMID:25026504 | | ||||||||||||||||||||||
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