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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 69057
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nr1i2
Name: nuclear receptor subfamily 1, group I, member 2
Acc ID: CHEBI:310312
Term: isoliquiritigenin
Definition: A member of the class of chalcones that is trans-chalcone hydroxylated at C-2', -4 and -4'.
Chemical ID: MESH:C040920
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nr1i2increases activityISORGD:691056480464CTDisoliquiritigenin results in increased activity of NR1I2 protein

PMID:29933105
Nr1i2increases expressionISORGD:691056480464CTDisoliquiritigenin results in increased expression of NR1I2 mRNA

PMID:29933105
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