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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 61853
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gpc1
Name: glypican 1
Acc ID: CHEBI:3090
Term: bicalutamide
Definition: A racemate comprising of equal amounts of (R)-bicalutamide and (S)-bicalutamide. It is an oral non-steroidal antiandrogen used in the treatment of prostate cancer and hirsutism.
Chemical ID: MESH:C053541
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
decreases expressionISORGD:7309306480464CTDbicalutamide results in decreased expression of GPC1 mRNA

PMID:15638997
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.