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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1315696
Species: Mus musculus
RGD Object: Gene
Symbol: Akr1c6
Name: aldo-keto reductase family 1, member C6
Acc ID: CHEBI:30853
Term: glycyrrhetinic acid
Definition: A pentacyclic triterpenoid that is olean-12-ene substituted by a hydroxy group at position 3, an oxo group at position 11 and a carboxy group at position 30.
Chemical ID: MESH:C119129
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Akr1c6decreases activityISOAKR1C4 (Homo sapiens)6480464CTDGlycyrrhetinic Acid results in decreased activity of AKR1C4 proteinPMID:12604236
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