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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 3761
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Sst
Name: somatostatin
Acc ID: CHEBI:3084
Term: bethanechol
Definition: The carbamic acid ester of 2-methylcholine. A slowly hydrolysed muscarinic agonist with no nicotinic effects, it is used as its chloride salt to increase smooth muscle tone, as in the gastrointestinal tract following abdominal surgery, treatment of gastro-oesophageal reflux disease, and as an alternative to catheterisation in the treatment of non-obstructive urinary retention.
Chemical ID: MESH:D018723
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Sstaffects secretionEXP 6480464CTDBethanechol affects the secretion of SST protein

PMID:19296048
Sstmultiple interactionsEXP 6480464CTDCALCA protein promotes the reaction [Bethanechol affects the secretion of SST protein]

PMID:19296048
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