Gene Chemical Interaction Report - Rat Genome Database

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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID:	737239
Species:	Homo sapiens
RGD Object:	Gene
Symbol:	FLG
Name:	filaggrin

Acc ID:	CHEBI:30817
Term:	trans-urocanic acid
Definition:	A urocanic acid in which the double bond of the carboxyethene moiety has E configuration.
Chemical ID:	MESH:D014560

Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.

Object Symbol	Qualifier	Evidence	With	Reference	Source	Notes	Original Reference(s)
FLG	decreases abundance	EXP		6480464	CTD	FLG mutant form results in decreased abundance of Urocanic Acid	PMID:24061166

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.