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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2670
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Gck
Name: glucokinase
Acc ID: CHEBI:30816
Term: vanillic acid
Definition: A monohydroxybenzoic acid that is 4-hydroxybenzoic acid substituted by a methoxy group at position 3.
Chemical ID: MESH:D014641
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gckmultiple interactionsISOGCK (Homo sapiens)6480464CTDVanillic Acid inhibits the reaction [INS protein results in decreased activity of GCK protein]; Vanillic Acid inhibits the reaction [INS protein results in decreased expression of GCK protein]PMID:33651899
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