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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1314946
Species: Mus musculus
RGD Object: Gene
Symbol: Nod2
Name: nucleotide-binding oligomerization domain containing 2
Acc ID: CHEBI:30805
Term: dodecanoic acid
Definition: A straight-chain, twelve-carbon medium-chain saturated fatty acid with strong bactericidal properties; the main fatty acid in coconut oil and palm kernel oil.
Chemical ID: MESH:C030358
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsISORGD:13149456480464CTDCurcumin inhibits the reaction [lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]], lauric acid promotes the reaction [NOD2 protein binds to NOD2 protein]

PMID:18413660
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.