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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10552
Species: Mus musculus
RGD Object: Gene
Symbol: Esr2
Name: estrogen receptor 2 (beta)
Acc ID: CHEBI:30772
Term: butyric acid
Definition: A straight-chain saturated fatty acid that is butane in which one of the terminal methyl groups has been oxidised to a carboxy group.
Chemical ID: MESH:D020148
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
increases expressionEXP 6480464CTDButyric Acid results in increased expression of ESR2 mRNA

PMID:22687346
multiple interactionsISORGD:692136480464CTDButyric Acid promotes the reaction [Estradiol results in increased activity of ESR2 protein]

PMID:15103026
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.