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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 1320489
Species: Homo sapiens
RGD Object: Gene
Symbol: HLCS
Name: holocarboxylase synthetase
Acc ID: CHEBI:30764
Term: 3-hydroxybenzoic acid
Definition: A monohydroxybenzoic acid that is benzoic acid substituted by a hydroxy group at position 3. It has been isolated from Taxus baccata. It is used as an intermediate in the synthesis of plasticisers, resins, pharmaceuticals, etc.
Chemical ID: MESH:C032948
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
HLCSdecreases activityEXP 6480464CTD3-hydroxybenzoic acid results in decreased activity of HLCS proteinPMID:26303405
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