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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2889
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Il18
Name: interleukin 18
Acc ID: CHEBI:30754
Term: anthranilic acid
Definition: An aminobenzoic acid that is benzoic acid having a single amino substituent located at position 2. It is a metabolite produced in L-tryptophan-kynurenine pathway in the central nervous system.
Chemical ID: MESH:C031385
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Il18multiple interactionsISOIL18 (Homo sapiens)6480464CTDanthranilic acid analog inhibits the reaction [IL18 protein results in increased secretion of IFNG protein]PMID:15799959
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