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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 10510
Species: Mus musculus
RGD Object: Gene
Symbol: Egf
Name: epidermal growth factor
Acc ID: CHEBI:30746
Term: benzoic acid
Definition: A compound comprising a benzene ring core carrying a carboxylic acid substituent.
Chemical ID: MESH:D019817
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTDBenzoic Acid analog inhibits the reaction [EGF protein promotes the reaction [STAT3 protein binds to EGFR protein]], Benzoic Acid analog inhibits the reaction [EGF protein results in increased phosphorylation of STAT3 protein]

PMID:26088127
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.