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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 62396
Species: Mus musculus
RGD Object: Gene
Symbol: Ddit3
Name: DNA-damage inducible transcript 3
Acc ID: CHEBI:30740
Term: ethylene glycol bis(2-aminoethyl)tetraacetic acid
Definition: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
Chemical ID: MESH:D004533
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
QualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
multiple interactionsEXP 6480464CTD[Egtazic Acid co-treated with 1, 2-bis(2-aminophenoxy)ethane-N, N, N', N'-tetraacetic acid] inhibits the reaction [Cadmium results in increased expression of DDIT3 protein], Egtazic Acid inhibits the reaction [Cadmium results in increased expression of DDIT3 protein]

PMID:29111403
multiple interactionsISORGD:691656480464CTDEgtazic Acid inhibits the reaction [Amiodarone results in increased expression of DDIT3]

PMID:21292685
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.