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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 620360
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Nfe2l2
Name: NFE2 like bZIP transcription factor 2
Acc ID: CHEBI:30740
Term: ethylene glycol bis(2-aminoethyl)tetraacetic acid
Definition: A diether that is ethylene glycol in which the hydrogens of the hydroxy groups have been replaced by 2-[bis(carboxymethyl)amino]ethyl group respectively.
Chemical ID: MESH:D004533
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Nfe2l2multiple interactionsISONFE2L2 (Homo sapiens)6480464CTDEgtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [CREBBP protein binds to NFE2L2 protein]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone promotes the reaction [NFE2L2 protein binds to HMOX1 promoter]]; Egtazic Acid inhibits the reaction [2-tert-butylhydroquinone results in increased activity of NFE2L2 protein]PMID:21443188
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