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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 70506
Species: Homo sapiens
RGD Object: Gene
Symbol: IGF1
Name: insulin like growth factor 1
Acc ID: CHEBI:30703
Term: tetrathiomolybdate(2-)
Definition: A molybdenum coordination entity that has formula MoS4.
Chemical ID: MESH:C020809
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
IGF1multiple interactionsEXP 6480464CTD[tetrathiomolybdate results in decreased activity of SOD1 protein] inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK1 protein]; [tetrathiomolybdate results in decreased activity of SOD1 protein] inhibits the reaction [IGF1 protein results in increased phosphorylation of MAPK3 protein]; tetrathiomolybdate inhibits the reaction [IGF1 protein results in increased phosphorylation of IGF1R protein]PMID:18480265
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