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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 734192
Species: Mus musculus
RGD Object: Gene
Symbol: Gpt
Name: glutamic pyruvic transaminase, soluble
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Gptincreases activityEXP 6480464CTDArsenic Trioxide results in increased activity of GPT proteinPMID:33846815
Gptmultiple interactionsEXP 6480464CTD18alpha,20beta-hydroxy-11-oxo-norolean-12-en-3beta-yl-2-O-beta-D-glucopyranurosyl-alpha-D-glucopyranosiduronate magnesium tetrahydrate inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]PMID:33846815
Gptincreases activityISOGpt (Rattus norvegicus)6480464CTDArsenic Trioxide results in increased activity of GPT proteinPMID:23283742
Gptincreases activityISOGPT (Homo sapiens)6480464CTDArsenic Trioxide results in increased activity of GPT proteinPMID:29751151
Gptincreases expressionISOGpt (Rattus norvegicus)6480464CTDArsenic Trioxide results in increased expression of GPT proteinPMID:28978146
Gptmultiple interactionsISOGpt (Rattus norvegicus)6480464CTDeriodictyol inhibits the reaction [Arsenic Trioxide results in increased expression of GPT protein]; naringenin inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]PMID:23283742 PMID:28978146
Gptmultiple interactionsISOGPT (Homo sapiens)6480464CTDDocosahexaenoic Acids inhibits the reaction [Arsenic Trioxide results in increased activity of GPT protein]PMID:29751151
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