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GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 733897
Species: Homo sapiens
RGD Object: Gene
Symbol: TH
Name: tyrosine hydroxylase
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
THdecreases expressionEXP 6480464CTDArsenic Trioxide results in decreased expression of TH proteinPMID:11027660
THdecreases expressionISOTh (Mus musculus)6480464CTDArsenic Trioxide results in decreased expression of TH mRNAPMID:23392890 PMID:23518225
THmultiple interactionsISOTh (Mus musculus)6480464CTDTaurine inhibits the reaction [Arsenic Trioxide results in decreased expression of TH mRNA]PMID:23392890
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