GENE - CHEMICAL INTERACTIONS REPORT
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction
is comprised of a complex set of reactions and/or regulatory events, possibly involving
additional chemicals and/or gene products.
Object Symbol | Qualifier | Evidence | With | Reference | Source | Notes | Original Reference(s) | Bid | multiple interactions | EXP | | 6480464 | CTD | Arsenic Trioxide promotes the reaction [Drugs, Chinese Herbal results in increased cleavage of BID protein] | PMID:28587418 | Bid | affects cleavage | ISO | BID (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide affects the cleavage of BID protein | PMID:15131059 | Bid | affects expression | ISO | Bid (Rattus norvegicus) | 6480464 | CTD | Arsenic Trioxide affects the expression of BID protein | PMID:18618274 | Bid | decreases expression | ISO | BID (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in decreased expression of BID protein | PMID:21418039 PMID:25574600 PMID:27430728 | Bid | increases activity | ISO | BID (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased activity of BID protein | PMID:20605902 | Bid | increases cleavage | ISO | BID (Homo sapiens) | 6480464 | CTD | Arsenic Trioxide results in increased cleavage of BID protein | PMID:10648417 PMID:19364129 PMID:25174355 | Bid | multiple interactions | ISO | BID (Homo sapiens) | 6480464 | CTD | [Arsenic Trioxide co-treated with Aprepitant] results in increased expression of BID mRNA; [Arsenic Trioxide co-treated with Curcumin] results in decreased expression of BID protein; [Arsenic Trioxide co-treated with Curcumin] results in increased expression of BID protein; [Arsenic Trioxide co-treated with esculetin] results in increased cleavage of BID protein; [Arsenic Trioxide co-treated with lonidamine] results in increased cleavage of and results in increased activity of BID protein; [Arsenic Trioxide co-treated with NVP-BKM120] results in increased expression of BID mRNA; [Arsenic Trioxide co-treated with Quercetin] results in increased cleavage of BID protein; [Arsenic Trioxide co-treated with TNF protein] results in increased cleavage of and results in increased activity of BID protein; Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein; Curcumin promotes the reaction [Arsenic Trioxide results in increased activity of BID protein]; Deoxyglucose promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; Genistein promotes the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; pyrazolanthrone promotes the reaction [Arsenic Trioxide results in increased cleavage of BID protein]; TP53 protein inhibits the reaction [Arsenic Trioxide results in increased cleavage of and results in increased activity of BID protein]; U 0126 promotes the reaction [Arsenic Trioxide results in increased cleavage of BID protein] | PMID:12851490 PMID:15665116 PMID:16972261 PMID:17673311 PMID:18359480 PMID:18546268 PMID:19428345 PMID:20605902 PMID:21889928 PMID:23041229 PMID:27430728 PMID:30145367 PMID:31539632 | | ||||||||||||||||||||||
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