Send us a Message



Submit Data |  Help |  Video Tutorials |  News |  Publications |  Download |  REST API |  Citing RGD |  Contact   

GENE - CHEMICAL INTERACTIONS REPORT

RGD ID: 2989
Species: Rattus norvegicus
RGD Object: Gene
Symbol: Lamp1
Name: lysosomal-associated membrane protein 1
Acc ID: CHEBI:30621
Term: diarsenic trioxide
Definition: An arsenic oxide in which arsenic and oxygen atoms are present in the ratio 2:3.
Chemical ID: MESH:C006632
Note: Use of the qualifier "multiple interactions" designates that the annotated interaction is comprised of a complex set of reactions and/or regulatory events, possibly involving additional chemicals and/or gene products.
Object SymbolQualifierEvidenceWithReferenceSourceNotesOriginal Reference(s)
Lamp1affects expressionISOLamp1 (Mus musculus)6480464CTDArsenic Trioxide affects the expression of LAMP1 proteinPMID:33462182
Lamp1increases expressionISOLamp1 (Mus musculus)6480464CTDArsenic Trioxide results in increased expression of LAMP1 mRNA; Arsenic Trioxide results in increased expression of LAMP1 proteinPMID:30237538 PMID:33462182
Lamp1increases expressionISOLAMP1 (Homo sapiens)6480464CTDArsenic Trioxide results in increased expression of LAMP1 mRNA; Arsenic Trioxide results in increased expression of LAMP1 proteinPMID:29307831
Lamp1multiple interactionsISOLamp1 (Mus musculus)6480464CTD3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; 3-methyladenine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; Acetylcysteine affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; Taurine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]PMID:30237538 PMID:33462182
Lamp1multiple interactionsISOLAMP1 (Homo sapiens)6480464CTDAcetylcysteine inhibits the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 mRNA]; TFEB protein affects the reaction [Arsenic Trioxide results in increased expression of LAMP1 protein]PMID:29307831
Go Back to source page   Continue to Ontology report